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Human Sexuality - The Effect of Diseases

Source: "Your Personal Medical and Sexual Problems" by Charles Osula, pp. 307 - 309.

Posted: March 10, 2008

Sexual response is adversely affected by stressful conditions, fatiguing work or exercise, mental depression, mental tension, heart break from unsuccessful business or being jilted by a loved one and various emotional distrubances whether arising from martial disharmony, divorce, loss of job, and involvement in criminal and legal proceedings.

These states demanding in their own right full attention and concentration exert negative influences on the well being of the individual and cause a diminished sexual motivation...we describe as a pre-requisite for good sexual response, a calm emotional state and self abandonment.

The way in which stresses disturb response is complex. When there is stress, the part of the brain called hypothalamus sends impulses to the part called pituitary. The pituitary decreases the supply of its hormones (F.S.H. and L.H.) This in turn causes a drop in the level of androgen (masculinizing hormone) manufactured by the testes. The consequence is that less pleasurable signals are transmitted to the sex centres located in the brain and so there is less sex urge and less sex response.

Again from our own study we have been able to establish that when there is stress, the body increases its content of a certain hormone called cortisone. Cortisone diminishes sexual interest since its activity is at variance with the activity of androgen, hormone that increases sex urge.

The inference from the foregoing is that when a patient has sexual problems and he is a victim of negative influences (stress, depression, etc), these negative influences should be treated before treatment to cure sexual difficulties is initiated.

Furthermore it is not uncommon for degenerative diseases as well as tumours and infections affecting the nerves in the waist (sacral nerves), and malnutrition to cause diminished sexual response.

Finally, diseases affecting the blood vessels are not uncommonly associated with destructive effects on sexual response. Thrombosis or blood clot may block the blood vessels carrying blood to the penis or vulva resulting in less blood supply to these part thus preventing vaso-congestion and erection in the male and swelling and lubrication in the female.

Hypertension is a common blood vessel disease and many drugs employed in the treatment of the disease and many drugs employed in the treatment of the disease can diminish sex drive, and can cause erectile failure and impotence.

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The effect of drugs on sexual activity has often been misinterpreted by many people. Some take drugs to alleviate shyness and thus remove sexual inhibition. In our own study many drugs exert deleterious effects on sexual response.

Alcohol and barbituates are centrally acting drugs, that is they act on the brain. Alcohol depresses brain centres which govern fear, and reduces anxiety, thus producing disinhibition. A larger dose of alcohol may however, impair cognitive functions before loss of consciousness. Small dose relax inhibition and therefore enhance sexual urge, but still higher doses will incapacitate a person and suppress sexual activity. Chronic alcoholism destroys sexual response because of debilitation. Similary chronic use of sedatives may diminish sexuality and so are some other drugs to which people may become addicted.

Sexual response, is adversely affected by various painful conditions, physical illnesses, diseases affecting the nerves, diseases affecting the blood vessels and diseases that affect the level of male hormones (androgen) in the body.

Sexual response results in a fiasco when the attempted intercourse is painful by virtue of local injuries. Pelvic inflammatory diseases, endometriosis, and the presence of Rheumatism, arthritis, large inguinal hernia and gross obesity can cause a deranged sexual response.

Sexual enjoyment is in serious jeopardy in the presence of debilitating illness such as diseases of the liver, and kidney and of course the presence of diabetes, multiple sclerosis, and tuberculosis and leprosy.

A man is a man by virtue of certain characteristics including the production of androgens by the testes. A woman is a woman by virtue of other characteristics including the production in the ovaries of special female hormones called oestrogen and progesterone.

Any treatment or operation necessitating the removal of the testes, or the use of drugs which reduce effective androgen level can cause a decrease sex urge and can cause failure of erection or impotence. Similarly if the pituitary gland which controls the function of the testes is diseased, sexual failure may occur.

The diseases that cause sexual failure may not necessarily always be of central origin. If the nerves that carry messages from the penis, the vulva, the testes and other genital parts are destroyed, requisite sexual signals cannot be transmitted to the brain and so sexual response is hampered. The blood flow to the sexual organs to cause vaso-congestion and erection, in the male or swelling and lubrication of the female may be highly reduced.

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